منابع مشابه
Inflammatory cells, ceramides, and expression of proteases in perivascular adipose tissue adjacent to human abdominal aortic aneurysms.
BACKGROUND Abdominal aortic aneurysm (AAA) is a deadly irreversible weakening and distension of the abdominal aortic wall. The pathogenesis of AAA remains poorly understood. Investigation into the physical and molecular characteristics of perivascular adipose tissue (PVAT) adjacent to AAA has not been done before and is the purpose of this study. METHODS AND RESULTS Human aortae, periaortic P...
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Background and Aim: A great interest for determining the particular mechanisms underlying lipogenesis and adipogenesis has been raised among researchers in order to fight obesity. We aimed to investigate the gene expression of FAS and its role in regulation of lipogenesis and adipogenesis in visceral adipose tissues from obese and normal-weight subjects. materials and Methods: A total of.parti...
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Protein tyrosine phosphatase interacting protein51 (PTPIP51) interacts both in vit ro and in v ivo withPTP1B, a protein tyrosine phosphatase involved in cellularregulation. PTPIP51 is known to be expressed in manydifferent types of tissues. It is involved in cellular processessuch as proliferation, differentiat ion and apoptosis. Never-theless, the exact cellular functio...
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The possible involvement of the evolutionarily conserved process of autophagy (selfeating) in the pathogenesis of human diseases has been increasingly appreciated in recent years. However, at present, many fundamental questions remain to be answered before autophagy can be considered as a therapeutic target: The biological consequences of activating or inhibiting the process are very much cell ...
متن کاملAdipose Tissue
Morphological changes associated with mobilization of lipid were studied in epididymal adipose tissue from fasted and from alloxan diabetic rats. In both groups of animals a decrease in lipid content was accompanied by the formation of complex frond-like cytoplasmic processes and of loops and folds of basement membrane which extended from cell surfaces. These changes, evident after 1 day of fas...
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ژورنال
عنوان ژورنال: Frontiers in Endocrinology
سال: 2020
ISSN: 1664-2392
DOI: 10.3389/fendo.2020.00407